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In the beginning…

I am in my 60s and have been using aging research to slow my aging. This blog is about the science behind what I and others are doing to live a healthier lifestyle and hopefully live until science defeats aging.

I am already doing a number of things to (hopefully) slow my aging. I am in my 60’s and over the last decade I have had a few age-related health problems. I have successfully fought off these problems, such as my rheumatoid arthritis; a herniated disk in my neck, cured without surgery; my occasional brain fog is gone; a tremor in my hand is mostly gone; vision problems where I mostly reversed growing farsightedness from my eye lenses getting stiffer and failing to focus on things I read. As I get older, I expect that conquering these issues will become increasingly difficult and the biohacking techniques I have been using will start to fail me. So far my health remains excellent, and with the many treatments coming for slowing the onset of aging diseases I am hoping to extend my health into late old age–and perhaps until aging can be reversed.

Continue reading “In the beginning…”

Daily Thesis Progress: January 2022

Background

1/2
Printed Prolonging healthy aging: Longevity vitamins and proteins, by Bruce Ames, 2018.

1/4
Started reading Ames, 2018.

1/5
In the morning I read a bit more of Ames 2018 paper.

Today my book Blind Analysis for Design of Experiments arrived. I ordered it last month. I browsed through it a bit.

1/6
Finished Ames.

1/7
I am not getting enough journal reading in so I think I will implement a policy of 1 article per week minimum.

Finished reading Ames 2018.

Reading in Xu, 20

Printed McCann (2018).

1/10
First class of Cellular Signaling, being taught by my advisor Larry Duffy. It is a 1 hour class meeting 3 times a week.

1/11
I spent most of the morning getting ready for the 2 pm meeting of the aging discussion group, and then an hour holding the discussion. 2 new non-local members, but not so many local members showed up. Total of about 7 of us.

1/12
Class in the morning (from 9:30 to 10:30).

After class I talked about my PhD project with Dr. Duffy.

In the evening I started reading a journal article … in the future I will try to do a better job of logging these (written 2/12/22 when I was reviewing these fir posting on my blog)

1/13
Protocol-Y meeting. Very good discussion. He is starting to put together his interview series for his documentary.

He requested books we liked, so I put together a list of my books. I spent quite a bit of time after the meeting doing so. I should link it here!

When I read an aging book I usually take handwritten notes on it. But a lot of these I haven’t transcribed. I figured Tom would find them useful (and perhaps other people) so I worked on my notes from reading Spring Chicken (which I thought was the best aging book I have read).

1/14
Class in the morning.

Finished entering my notes from Spring Chicken.

Started reading Kappele’s Blind Analysis for Design of Experiments and Response Surface Methodology, chapter 1 & 2 and browsed through the appendix.

1/18
Found several interesting papers, printed 3 of them and read one

1/19
Read chapter 3 of Kappele’s Blind Analysis for Design of Experiments and Response Surface Methodology.

After a day off Monday, had class today.

In the afternoon I worked on my thesis project proposal.

1/20
Spent most of the day working on my proposal for an experiment. Did a little bit more work on my reading log, getting more information entered.

Short entry for a ton of work!

1/21
Cellular Signaling class, 9:30 to 10:30. This class actually works really well with my schedule because I drop my daughter off at 9:15 for her class in Gruening. She finishes in time to walk up to my classroom in Reichardt by the time I get out.

Aging books, by author:

This page was started when a friend asked for a list of my aging books. He has begun to put together a documentary about aging and rejuvenation, and I am one of his advisors. I generated this list from my list of books in my library (which happens to exceed 2,000). It turns out I have more than 40. I took notes on about half of these, and of these about 1/4 are online (those that are online are linked; just click the title).

Alternative list in my Ray’s Readings page, which has better descriptions but only includes the books I have entered the notes for.

This was last updated in January 2022.

Agus, David B. MDA Short Guide to a Long Life
Amen, Daniel G. MDUse Your Brain to Change Your Age
Anton, TedThe Longevity Seekers
Austad, StevenWhy We Age
Beers, Mark H. (M.D.) and Robert Berkow, M. D. (editors)The Merck Manual of Geriatrics
Ben BovaImmortality: How Science is Extending Your Live Span–and Changing the World
Blastland, MichaelThe Norm Chronicles
Bredesen, Dale E. MDThe End of Alzheimer’s
Buettner, DanThe Blue Zones
Calton, Mira CN; Jayson Calton, PhDRebuild Your Bones
Clark, William R.A Means to an End: The biological Basis of Aging and Death
Cold Spring Harbour LaboratoryMechanisms of Aging
Crowley, Chris & Henry S. Lodge MDYounger Next Year: Live Strong, Fit and Sexy–Until You’re 80 and Beyond
Dawkings, RichardThe Blind Watchmaker
de Grey, AubreyEnding Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in Our Lifetime
Evans, William & Irwing RosenbergBiomarkers: The 10 Dertminants of Aging You Can Control
Finch, Caleb E.Longevity, Senescence, and the Genome
Finch, Caleb E.The Biology of Human Longevity
Finch, Caleb E. and Thomas B. L. KirkwoodChance, Development, and Aging
Friedman, S. Howard and Martin, R. LeslieThe Longevity Project
Gifford, BillSpring Chicken: Stay Young Forever (or die trying)
Gittleman, Ann Louise PhDRadical Longevity
Gundry, Steven R. MDThe Longevity Paradox
Kaeberlein, R. Matt and Martin, M. GeorgeThe Biology of Aging
Kastner, JosephA species of eternity
Kelder, PeterAncient Secret of the Fountain of Youth
Kirkwood, TomTime of Our Lives
Kurzweil, Ray and Terry GrossmanFantastic Voyage: Live Long Enough to Live Forever
Longo, Valter PhDThe Longevity Diet
Masoro, Edward J. & Steven N. AustadHandbook of the Biology of Aging, 5th Edition
Masoro, Edward J. & Steven N. AustadHandbook of the Biology of Aging, 6th Edition
Medine, John J.The Clock of Ages
Metzl, JamieHacking Darwin: Genetic Engineering and the Future of Humanity
Mitteldorf, JoshCracking the Aging Code
Mosley, Dr. MichaelThe Fast Life
Olshansky, S. Jay and Bruce A. CarnesThe Quest for Immortality
Reynolds, Siimon365 Ways to Live to 100
Ridley, MattGenome
Robbins, JohnHealthy at 100
Sinclair, David A.Lifespan: Why We Age-and Why We Don’t Have To
Stipp, DavidThe Youth Pill: Scientists at the brink of an anti-aging revolution
Walford, Roy L. MDThe Anti-Aging Plan
Walford, Roy L. MDThe 120 Year Diet
Weindruch, Richard & Walford, L. Roy M.D.The Retardation of Aging And Disease By Dietary Restriction
West, MichaelThe Immortal Cell
AuthorTitleHow Well I Liked
Robbins, JohnHealthy at 100Fair

Update spring 2020

Due to business constraints  that resulted from taking last summer (2019) off and taking a cruise around the world I have not had time to work on this much.  When we got home our rental vacancy rate was 30% and as a result I spent all winter working 60 hours a week.  Things were finally starting to get back to normal when COVID-19 hit.

I would have managed to do a lot of work on this during lockdown–except at the end of March I had a perforated appendix/appendicitis and then as soon as that had started to heal my incision got infected.  So the last month I have done little besides engage in one of my favorite hobbies: reading.  I kind of went overboard and read 46 books in the last month!

Now (end of April) I am finally starting to feel up to doing a little work.  So I started by ‘attending’ a virtual conference on aging: Longevity 2020 (https://www.longevity.technology/).  The conference started Monday and goes through May 1.  It was very well put together and I am really getting a lot of information from the 2.5 to 3 hours of presentation.  I have been getting about 18 pages of notes every day; the information presented is (as in most conferences) very dense.

Also this year I began a local Aging Discussion Group.  We held 2 meetings before COVID-19 prevented further meetings.  I hope to resume meetings as soon as it is safe for us to do so.  Most of the people who joined are older and so it is very important that getting together to learn about aging doesn’t shorten our lifespan by catching COVID-19!

I have complete notes from the first 2 meetings, which was really the same meeting with 2 different groups of people.  I really enjoyed these and hope I managed to present information the group will help them plan for a healthy life.  If you are local and interested in joining the group please get in touch.